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A bacterial encoded protein induces extreme multinucleation and cell-cell internalization in intestinal cells
Despite extensive study, the molecular mechanisms that lead to multinucleation and cell enlargement (hypertrophy) remain poorly understood. Here, we show that a single bacterial virulence protein, EspF, from the human pathogen enteropathogenic E. coli induces extreme multi-nucleation in small intest...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879132/ https://www.ncbi.nlm.nih.gov/pubmed/24665371 http://dx.doi.org/10.4161/tisb.22639 |