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Multi-tissue Analysis of Co-expression Networks by Higher-Order Generalized Singular Value Decomposition Identifies Functionally Coherent Transcriptional Modules

Recent high-throughput efforts such as ENCODE have generated a large body of genome-scale transcriptional data in multiple conditions (e.g., cell-types and disease states). Leveraging these data is especially important for network-based approaches to human disease, for instance to identify coherent...

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Detalles Bibliográficos
Autores principales: Xiao, Xiaolin, Moreno-Moral, Aida, Rotival, Maxime, Bottolo, Leonardo, Petretto, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879165/
https://www.ncbi.nlm.nih.gov/pubmed/24391511
http://dx.doi.org/10.1371/journal.pgen.1004006