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A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants Identifies a Novel Factor Involved in Cell Wall Precursor Metabolism

The cell envelope of Gram-negative bacteria is a formidable barrier that is difficult for antimicrobial drugs to penetrate. Thus, the list of treatments effective against these organisms is small and with the rise of new resistance mechanisms is shrinking rapidly. New therapies to treat Gram-negativ...

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Detalles Bibliográficos
Autores principales: Paradis-Bleau, Catherine, Kritikos, George, Orlova, Katya, Typas, Athanasios, Bernhardt, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879167/
https://www.ncbi.nlm.nih.gov/pubmed/24391520
http://dx.doi.org/10.1371/journal.pgen.1004056