Cargando…
Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching
BACKGROUND: RNA-seq is now widely used to quantitatively assess gene expression, expression differences and isoform switching, and promises to deliver results for the entire transcriptome. However, whether the transcriptional state of a gene can be captured accurately depends critically on library p...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879183/ https://www.ncbi.nlm.nih.gov/pubmed/24365034 http://dx.doi.org/10.1186/1471-2105-14-370 |