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Cortactin regulates the activity of small GTPases and ICAM-1 clustering in endothelium: Implications for the formation of docking structures

Cortactin is an actin-binding molecule that regulates various cellular processes requiring actin dynamics. We recently described cortactin-deficient mice and despite its pivotal role for actin remodeling in vitro, these mice are surprisingly healthy. Analyzing cortactin functions in endothelium unde...

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Detalles Bibliográficos
Autores principales: Vestweber, Dietmar, Zeuschner, Dagmar, Rottner, Klemens, Schnoor, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879184/
https://www.ncbi.nlm.nih.gov/pubmed/24665381
http://dx.doi.org/10.4161/tisb.23862