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A technique for quantifying intracellular free sodium ion using a microplate reader in combination with sodium-binding benzofuran isophthalate and probenecid in cultured neonatal rat cardiomyocytes
BACKGROUND: Intracellular sodium ([Na(+)](i)) kinetics are involved in cardiac diseases including ischemia, heart failure, and hypertrophy. Because [Na(+)](i) plays a crucial role in modulating the electrical and contractile activity in the heart, quantifying [Na(+)](i) is of great interest. Using f...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879185/ https://www.ncbi.nlm.nih.gov/pubmed/24369990 http://dx.doi.org/10.1186/1756-0500-6-556 |