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E2A suppresses invasion and migration by targeting YAP in colorectal cancer cells

BACKGROUND: E2A gene, which encodes two basic helix–loop–helix (bHLH) transcription factors E12 and E47, has been identified as regulator of B lymphoid hematopoiesis and suppressor of lymphoma. E47 protein was found to decrease E-cadherin expression and induce epithelial-mesenchymal transition (EMT)...

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Detalles Bibliográficos
Autores principales: Zhao, Hongchao, Huang, Ao, Li, Pu, Quan, Yingjun, Feng, Bo, Chen, Xuehua, Mao, Zhihai, Zhu, Zhenggang, Zheng, Minhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879192/
https://www.ncbi.nlm.nih.gov/pubmed/24369055
http://dx.doi.org/10.1186/1479-5876-11-317