Subtle Changes in Motif Positioning Cause Tissue-Specific Effects on Robustness of an Enhancer's Activity

Deciphering the specific contribution of individual motifs within cis-regulatory modules (CRMs) is crucial to understanding how gene expression is regulated and how this process is affected by sequence variation. But despite vast improvements in the ability to identify where transcription factors (T...

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Detalles Bibliográficos
Autores principales: Erceg, Jelena, Saunders, Timothy E., Girardot, Charles, Devos, Damien P., Hufnagel, Lars, Furlong, Eileen E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879207/
https://www.ncbi.nlm.nih.gov/pubmed/24391522
http://dx.doi.org/10.1371/journal.pgen.1004060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879207/
https://www.ncbi.nlm.nih.gov/pubmed/24391522
http://dx.doi.org/10.1371/journal.pgen.1004060

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