MicroRNA-208a Increases Myocardial Fibrosis via Endoglin in Volume Overloading Heart

MicroRNA-208a (mir-208a) is essential for cardiac hypertrophy and fibrosis. Endoglin, a co-receptor of transforming growth factor-β is also essential for cardiac fibrosis. Endoglin has been shown to be a target of mir-208a in the in vitro mechanical stress model. Volume overload can lead to heart fa...

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Detalles Bibliográficos
Autores principales: Wang, Bao-Wei, Wu, Gong-Jhe, Cheng, Wen-Ping, Shyu, Kou-Gi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879305/
https://www.ncbi.nlm.nih.gov/pubmed/24392114
http://dx.doi.org/10.1371/journal.pone.0084188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879305/
https://www.ncbi.nlm.nih.gov/pubmed/24392114
http://dx.doi.org/10.1371/journal.pone.0084188

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