Cargando…

WRB and CAML Are Necessary and Sufficient to Mediate Tail-Anchored Protein Targeting to the ER Membrane

Tail-Anchored (TA) proteins are inserted into the endoplasmic reticulum (ER) membrane of yeast cells via the posttranslational Guided Entry of Tail-Anchored protein (GET) pathway. The key component of this targeting machinery is the ATPase Get3 that docks to the ER membrane by interacting with a rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Vilardi, Fabio, Stephan, Milena, Clancy, Anne, Janshoff, Andreas, Schwappach, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879356/
https://www.ncbi.nlm.nih.gov/pubmed/24392163
http://dx.doi.org/10.1371/journal.pone.0085033