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WRB and CAML Are Necessary and Sufficient to Mediate Tail-Anchored Protein Targeting to the ER Membrane
Tail-Anchored (TA) proteins are inserted into the endoplasmic reticulum (ER) membrane of yeast cells via the posttranslational Guided Entry of Tail-Anchored protein (GET) pathway. The key component of this targeting machinery is the ATPase Get3 that docks to the ER membrane by interacting with a rec...
Autores principales: | Vilardi, Fabio, Stephan, Milena, Clancy, Anne, Janshoff, Andreas, Schwappach, Blanche |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879356/ https://www.ncbi.nlm.nih.gov/pubmed/24392163 http://dx.doi.org/10.1371/journal.pone.0085033 |
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