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STING-Dependent Type I IFN Production Inhibits Cell-Mediated Immunity to Listeria monocytogenes
Infection with Listeria monocytogenes strains that enter the host cell cytosol leads to a robust cytotoxic T cell response resulting in long-lived cell-mediated immunity (CMI). Upon entry into the cytosol, L. monocytogenes secretes cyclic diadenosine monophosphate (c-di-AMP) which activates the inna...
Autores principales: | Archer, Kristina A., Durack, Juliana, Portnoy, Daniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879373/ https://www.ncbi.nlm.nih.gov/pubmed/24391507 http://dx.doi.org/10.1371/journal.ppat.1003861 |
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