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Strong Heterogeneity in Mutation Rate Causes Misleading Hallmarks of Natural Selection on Indel Mutations in the Human Genome
Elucidating the mechanisms of mutation accumulation and fixation is critical to understand the nature of genetic variation and its contribution to genome evolution. Of particular interest is the effect of insertions and deletions (indels) on the evolution of genome landscapes. Recent population-scal...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879449/ https://www.ncbi.nlm.nih.gov/pubmed/24113537 http://dx.doi.org/10.1093/molbev/mst185 |