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Contribution of Selection for Protein Folding Stability in Shaping the Patterns of Polymorphisms in Coding Regions
The patterns of polymorphisms in genomes are imprints of the evolutionary forces at play in nature. In particular, polymorphisms have been extensively used to infer the fitness effects of mutations and their dynamics of fixation. However, the role and contribution of molecular biophysics to these ob...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879451/ https://www.ncbi.nlm.nih.gov/pubmed/24124208 http://dx.doi.org/10.1093/molbev/mst189 |