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Mutant p53 Regulates Dicer through p63-dependent and -independent Mechanisms to Promote an Invasive Phenotype

The control and processing of microRNAs (miRs) is critical in the regulation of all cellular responses. Previous studies have suggested that a reduction in the expression of certain miRs, or an overall decrease in miR processing through the partial depletion of Dicer, can promote enhanced metastatic...

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Detalles Bibliográficos
Autores principales: Muller, Patricia A. J., Trinidad, Antonio G., Caswell, Patrick T., Norman, Jim C., Vousden, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879536/
https://www.ncbi.nlm.nih.gov/pubmed/24220032
http://dx.doi.org/10.1074/jbc.M113.502138