Stabilization of the Dimeric Birch Pollen Allergen Bet v 1 Impacts Its Immunological Properties

Many allergens share several biophysical characteristics, including the capability to undergo oligomerization. The dimerization mechanism in Bet v 1 and its allergenic properties are so far poorly understood. Here, we report crystal structures of dimeric Bet v 1, revealing a noncanonical incorporati...

Descripción completa

Detalles Bibliográficos
Autores principales: Kofler, Stefan, Ackaert, Chloé, Samonig, Martin, Asam, Claudia, Briza, Peter, Horejs-Hoeck, Jutta, Cabrele, Chiara, Ferreira, Fatima, Duschl, Albert, Huber, Christian, Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879576/
https://www.ncbi.nlm.nih.gov/pubmed/24253036
http://dx.doi.org/10.1074/jbc.M113.518795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879576/
https://www.ncbi.nlm.nih.gov/pubmed/24253036
http://dx.doi.org/10.1074/jbc.M113.518795

Ejemplares similares