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Characterization of a Novel Transgenic Mouse Tumor Model for Targeting HER2+ Cancer Stem Cells

HER2 is an oncogenic tumor-associated antigen overexpressed in 20-25% of breast cancers, which is associated with increased invasion, metastasis of the disease and resistance to therapy. Recent studies have further shown that HER2 can increase the population of breast cancer stem cells (BCSCs). Howe...

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Detalles Bibliográficos
Autores principales: Wang, Su He, Lu, Lin, Fan, Yongyi, Wicha, Max S., Cao, Zhengyi, Chang, Alfred E., Xia, Jian-chuan, Baker Jr., James R., Li, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879588/
https://www.ncbi.nlm.nih.gov/pubmed/24391448
http://dx.doi.org/10.7150/ijbs.6309