Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome

BACKGROUND: The presence of an extra whole or part of chromosome 21 in people with Down syndrome (DS) is associated with multiple neurological changes, including pathological aging that often meets the criteria for Alzheimer’s Disease (AD). In addition, trisomies have been shown to disrupt normal ep...

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Detalles Bibliográficos
Autores principales: Jones, Meaghan J, Farré, Pau, McEwen, Lisa M, MacIsaac, Julia L, Watt, Kim, Neumann, Sarah M, Emberly, Eldon, Cynader, Max S, Virji-Babul, Naznin, Kobor, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879645/
https://www.ncbi.nlm.nih.gov/pubmed/24373378
http://dx.doi.org/10.1186/1755-8794-6-58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879645/
https://www.ncbi.nlm.nih.gov/pubmed/24373378
http://dx.doi.org/10.1186/1755-8794-6-58

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