Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling

Angiogenesis defines the process in which new vessels grow from existing vessels. Using the mouse retina as a model system, we show that cysteine-rich motor neuron 1 (Crim1), a type I transmembrane protein, is highly expressed in angiogenic endothelial cells. Conditional deletion of the Crim1 gene i...

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Detalles Bibliográficos
Autores principales: Fan, Jieqing, Ponferrada, Virgilio G., Sato, Tomohito, Vemaraju, Shruti, Fruttiger, Marcus, Gerhardt, Holger, Ferrara, Napoleone, Lang, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879820/
https://www.ncbi.nlm.nih.gov/pubmed/24353059
http://dx.doi.org/10.1242/dev.097949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879820/
https://www.ncbi.nlm.nih.gov/pubmed/24353059
http://dx.doi.org/10.1242/dev.097949

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