A ROCK Inhibitor Blocks the Inhibitory Effect of Chondroitin Sulfate Proteoglycan on Morphological Changes of Mesenchymal Stromal/Stem Cells into Neuron-Like Cells

Chondroitin sulfate proteoglycan (CSPG) inhibits neurite outgrowth of various neuronal cell types, and CSPG-associated inhibition of neurite outgrowth is mediated by the Rho/ROCK pathway. Mesenchymal stromal/stem cells (MSCs) have the potential to differentiate into neuron-like cells under specific...

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Detalles Bibliográficos
Autores principales: Lim, Hee-Suk, Joe, Young Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879916/
https://www.ncbi.nlm.nih.gov/pubmed/24404335
http://dx.doi.org/10.4062/biomolther.2013.041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879916/
https://www.ncbi.nlm.nih.gov/pubmed/24404335
http://dx.doi.org/10.4062/biomolther.2013.041

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