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Evaluation of Luminescent P450 Analysis for Directed Evolution of Human CYP4A11

Cytochrome P450 4A11 (CYP4A11) is a fatty acid hydroxylase enzyme expressed in human liver. It catalyzes not only the hydroxylation of saturated and unsaturated fatty acids, but the conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), a regulator of blood pressure. In this st...

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Detalles Bibliográficos
Autores principales: Choi, Seunghye, Han, Songhee, Lee, Hwayoun, Chun, Young-Jin, Kim, Donghak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879922/
https://www.ncbi.nlm.nih.gov/pubmed/24404341
http://dx.doi.org/10.4062/biomolther.2013.086