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Why Are Genes Encoded on the Lagging Strand of the Bacterial Genome?
Genomic DNA is used as the template for both replication and transcription, whose machineries may collide and result in mutagenesis, among other damages. Because head-on collisions are more deleterious than codirectional collisions, genes should be preferentially encoded on the leading strand to avo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879979/ https://www.ncbi.nlm.nih.gov/pubmed/24273314 http://dx.doi.org/10.1093/gbe/evt193 |