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Ischemia-induced cell depolarization: does the hyperpolarization-activated cation channel HCN2 affect the outcome after stroke in mice?

BACKGROUND: Brain ischemia is known to include neuronal cell death and persisting neurological deficits. A lack of oxygen and glucose are considered to be key mediators of ischemic neurodegeneration while the exact mechanisms are yet unclear. In former studies the expression of two different two-por...

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Detalles Bibliográficos
Autores principales: Ehling, Petra, Göb, Eva, Bittner, Stefan, Budde, Thomas, Ludwig, Andreas, Kleinschnitz, Christoph, Meuth, Sven G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879998/
https://www.ncbi.nlm.nih.gov/pubmed/24373160
http://dx.doi.org/10.1186/2040-7378-5-16