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T cell-activation in neuromyelitis optica lesions plays a role in their formation

BACKGROUND: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system (CNS), which is characterized by the presence of pathogenic serum autoantibodies against aquaporin 4 (AQP4) in the vast majority of patients. The contribution of T cells to the formation of...

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Detalles Bibliográficos
Autores principales: Pohl, Maria, Kawakami, Naoto, Kitic, Maja, Bauer, Jan, Martins, Rui, Fischer, Marie-Therese, Machado-Santos, Joana, Mader, Simone, Ellwart, Joachim W, Misu, Tatsuro, Fujihara, Kazuo, Wekerle, Hartmut, Reindl, Markus, Lassmann, Hans, Bradl, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879999/
https://www.ncbi.nlm.nih.gov/pubmed/24367907
http://dx.doi.org/10.1186/2051-5960-1-85