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HTLV-1 bZIP factor supports proliferation of adult T cell leukemia cells through suppression of C/EBPα signaling

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus etiologically associated with adult T-cell leukemia (ATL). The HTLV-1 bZIP factor (HBZ), which is encoded by minus strand of provirus, is expressed in all ATL cases and supports the proliferation of ATL cells. However...

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Detalles Bibliográficos
Autores principales: Zhao, Tiejun, Coutts, Aaron, Xu, Lingling, Yu, Juntao, Ohshima, Koichi, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880043/
https://www.ncbi.nlm.nih.gov/pubmed/24359396
http://dx.doi.org/10.1186/1742-4690-10-159