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Analyzing Protein Micro-Heterogeneity in Chicken Ovalbumin by High-Resolution Native Mass Spectrometry Exposes Qualitatively and Semi-Quantitatively 59 Proteoforms

[Image: see text] Taking chicken Ovalbumin as a prototypical example of a eukaryotic protein we use high-resolution native electrospray ionization mass spectrometry on a modified Exactive Orbitrap mass analyzer to qualitatively and semiquantitatively dissect 59 proteoforms in the natural protein. Th...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Barendregt, Arjan, Kamerling, Johannis P., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880056/
https://www.ncbi.nlm.nih.gov/pubmed/24229052
http://dx.doi.org/10.1021/ac403057y