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Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice

BACKGROUND: Illuminating the role of the microtubule-associated protein tau in neurodegenerative diseases is of increasing importance, supported by recent studies establishing novel functions of tau in synaptic signalling and cytoskeletal organization. In severe dementias like Alzheimer’s disease (A...

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Detalles Bibliográficos
Autores principales: Hoffmann, Nadine A, Dorostkar, Mario M, Blumenstock, Sonja, Goedert, Michel, Herms, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880070/
https://www.ncbi.nlm.nih.gov/pubmed/24344647
http://dx.doi.org/10.1186/2051-5960-1-82