Cargando…

Differential inhibition of LINE1 and LINE2 retrotransposition by vertebrate AID/APOBEC proteins

BACKGROUND: The role of AID/APOBEC proteins in the mammalian immune response against retroviruses and retrotransposons is well established. G to A hypermutations, the hallmark of their cytidine deaminase activity, are present in several mammalian retrotransposons. However, the role of AID/APOBEC pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Lindič, Nataša, Budič, Maruška, Petan, Toni, Knisbacher, Binyamin A, Levanon, Erez Y, Lovšin, Nika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880073/
https://www.ncbi.nlm.nih.gov/pubmed/24344916
http://dx.doi.org/10.1186/1742-4690-10-156