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Differential inhibition of LINE1 and LINE2 retrotransposition by vertebrate AID/APOBEC proteins
BACKGROUND: The role of AID/APOBEC proteins in the mammalian immune response against retroviruses and retrotransposons is well established. G to A hypermutations, the hallmark of their cytidine deaminase activity, are present in several mammalian retrotransposons. However, the role of AID/APOBEC pro...
Autores principales: | Lindič, Nataša, Budič, Maruška, Petan, Toni, Knisbacher, Binyamin A, Levanon, Erez Y, Lovšin, Nika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880073/ https://www.ncbi.nlm.nih.gov/pubmed/24344916 http://dx.doi.org/10.1186/1742-4690-10-156 |
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