A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by the deposition of insoluble amyloid plaques in the neuropil composed of highly stable, self-assembled Amyloid-beta (Aβ) fibrils. Copper has been implicated to play a role in Alzheimer’s disease. Dimers of Aβ have been isolated from AD brain an...

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Detalles Bibliográficos
Autores principales: Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William Grant, Morris, Kyle L, Sada, Alaa Abdul, Thorpe, Julian R, Serpell, Louise C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880074/
https://www.ncbi.nlm.nih.gov/pubmed/24351276
http://dx.doi.org/10.1186/2051-5960-1-83

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880074/
https://www.ncbi.nlm.nih.gov/pubmed/24351276
http://dx.doi.org/10.1186/2051-5960-1-83

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