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A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is characterized by the deposition of insoluble amyloid plaques in the neuropil composed of highly stable, self-assembled Amyloid-beta (Aβ) fibrils. Copper has been implicated to play a role in Alzheimer’s disease. Dimers of Aβ have been isolated from AD brain an...
Autores principales: | Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William Grant, Morris, Kyle L, Sada, Alaa Abdul, Thorpe, Julian R, Serpell, Louise C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880074/ https://www.ncbi.nlm.nih.gov/pubmed/24351276 http://dx.doi.org/10.1186/2051-5960-1-83 |
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