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Restoration of LRIG1 suppresses bladder cancer cell growth by directly targeting EGFR activity

BACKGROUND: Recently, leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1), a negative regulator of EGFR, was discovered is a novel agent for suppressing bladder cancer. The aim of this study was to investigate the impact of LRIG1 on the biological features of aggressive bladder cancer cel...

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Detalles Bibliográficos
Autores principales: Chang, Lei, Shi, Runlin, Yang, Tao, Li, Fan, Li, Guohao, Guo, Yonglian, Lang, Bin, Yang, Weimin, Zhuang, Qianyuan, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880093/
https://www.ncbi.nlm.nih.gov/pubmed/24314030
http://dx.doi.org/10.1186/1756-9966-32-101