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Restoration of LRIG1 suppresses bladder cancer cell growth by directly targeting EGFR activity
BACKGROUND: Recently, leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1), a negative regulator of EGFR, was discovered is a novel agent for suppressing bladder cancer. The aim of this study was to investigate the impact of LRIG1 on the biological features of aggressive bladder cancer cel...
Autores principales: | Chang, Lei, Shi, Runlin, Yang, Tao, Li, Fan, Li, Guohao, Guo, Yonglian, Lang, Bin, Yang, Weimin, Zhuang, Qianyuan, Xu, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880093/ https://www.ncbi.nlm.nih.gov/pubmed/24314030 http://dx.doi.org/10.1186/1756-9966-32-101 |
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