High-throughput genome scaffolding from in-vivo DNA interaction frequency

Despite advances in DNA-sequencing technology, assembly of complex genomes remains a major challenge, particularly for genomes sequenced using short reads, which yield highly fragmented assemblies. Here we show that genome-wide in vivo chromatin interaction frequency data, which are measurable with...

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Detalles Bibliográficos
Autores principales: Kaplan, Noam, Dekker, Job
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880131/
https://www.ncbi.nlm.nih.gov/pubmed/24270850
http://dx.doi.org/10.1038/nbt.2768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880131/
https://www.ncbi.nlm.nih.gov/pubmed/24270850
http://dx.doi.org/10.1038/nbt.2768

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