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High-throughput genome scaffolding from in-vivo DNA interaction frequency
Despite advances in DNA-sequencing technology, assembly of complex genomes remains a major challenge, particularly for genomes sequenced using short reads, which yield highly fragmented assemblies. Here we show that genome-wide in vivo chromatin interaction frequency data, which are measurable with...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880131/ https://www.ncbi.nlm.nih.gov/pubmed/24270850 http://dx.doi.org/10.1038/nbt.2768 |