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Preparation, characterization and optimization of sildenafil citrate loaded PLGA nanoparticles by statistical factorial design

BACKGROUND AND THE AIM OF THE STUDY: The objective of the present study was to formulate and optimize nanoparticles (NPs) of sildenafil-loaded poly (lactic-co-glycolic acid) (PLGA) by double emulsion solvent evaporation (DESE) method. The relationship between design factors and experimental data was...

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Detalles Bibliográficos
Autores principales: Ghasemian, Elham, Vatanara, Alireza, Rouholamini Najafabadi, Abdolhossein, Rouini, Mohammad Reza, Gilani, Kambiz, Darabi, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880179/
https://www.ncbi.nlm.nih.gov/pubmed/24355133
http://dx.doi.org/10.1186/2008-2231-21-68