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Microfluidic Thrombosis under Multiple Shear Rates and Antiplatelet Therapy Doses

The mainstay of treatment for thrombosis, the formation of occlusive platelet aggregates that often lead to heart attack and stroke, is antiplatelet therapy. Antiplatelet therapy dosing and resistance are poorly understood, leading to potential incorrect and ineffective dosing. Shear rate is also su...

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Detalles Bibliográficos
Autores principales: Li, Melissa, Hotaling, Nathan A., Ku, David N., Forest, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880267/
https://www.ncbi.nlm.nih.gov/pubmed/24404131
http://dx.doi.org/10.1371/journal.pone.0082493