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Computational Modeling of 3D Tumor Growth and Angiogenesis for Chemotherapy Evaluation

Solid tumors develop abnormally at spatial and temporal scales, giving rise to biophysical barriers that impact anti-tumor chemotherapy. This may increase the expenditure and time for conventional drug pharmacokinetic and pharmacodynamic studies. In order to facilitate drug discovery, we propose a m...

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Detalles Bibliográficos
Autores principales: Tang, Lei, van de Ven, Anne L., Guo, Dongmin, Andasari, Vivi, Cristini, Vittorio, Li, King C., Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880288/
https://www.ncbi.nlm.nih.gov/pubmed/24404145
http://dx.doi.org/10.1371/journal.pone.0083962