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Green Tea and One of Its Constituents, Epigallocatechine-3-gallate, Are Potent Inhibitors of Human 11β-hydroxysteroid Dehydrogenase Type 1

The microsomal enzyme 11β-hydroxysteroid deydrogenase type 1 (11β-HSD1) catalyzes the interconversion of glucocorticoid receptor-inert cortisone to receptor- active cortisol, thereby acting as an intracellular switch for regulating the access of glucocorticoid hormones to the glucocorticoid receptor...

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Detalles Bibliográficos
Autores principales: Hintzpeter, Jan, Stapelfeld, Claudia, Loerz, Christine, Martin, Hans-Joerg, Maser, Edmund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880318/
https://www.ncbi.nlm.nih.gov/pubmed/24404164
http://dx.doi.org/10.1371/journal.pone.0084468