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Green Tea and One of Its Constituents, Epigallocatechine-3-gallate, Are Potent Inhibitors of Human 11β-hydroxysteroid Dehydrogenase Type 1
The microsomal enzyme 11β-hydroxysteroid deydrogenase type 1 (11β-HSD1) catalyzes the interconversion of glucocorticoid receptor-inert cortisone to receptor- active cortisol, thereby acting as an intracellular switch for regulating the access of glucocorticoid hormones to the glucocorticoid receptor...
Autores principales: | Hintzpeter, Jan, Stapelfeld, Claudia, Loerz, Christine, Martin, Hans-Joerg, Maser, Edmund |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880318/ https://www.ncbi.nlm.nih.gov/pubmed/24404164 http://dx.doi.org/10.1371/journal.pone.0084468 |
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