Distinct Cyclosporin A Doses Are Required to Enhance Bone Formation Induced by Cyclic and Rest-Inserted Loading in the Senescent Skeleton

Age-related decline in periosteal adaptation negatively impacts the ability to utilize exercise to enhance bone mass and strength in the elderly. We recently observed that in senescent animals subject to cyclically applied loading, supplementation with Cyclosporin A (CsA) substantially enhanced the...

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Detalles Bibliográficos
Autores principales: Srinivasan, Sundar, Threet, Dewayne, Worton, Leah E., Ausk, Brandon J., Bain, Steven D., Gardiner, Edith M., Kwon, Ronald Y., Gross, Ted S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880323/
https://www.ncbi.nlm.nih.gov/pubmed/24404194
http://dx.doi.org/10.1371/journal.pone.0084868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880323/
https://www.ncbi.nlm.nih.gov/pubmed/24404194
http://dx.doi.org/10.1371/journal.pone.0084868

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