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Distinct Cyclosporin A Doses Are Required to Enhance Bone Formation Induced by Cyclic and Rest-Inserted Loading in the Senescent Skeleton
Age-related decline in periosteal adaptation negatively impacts the ability to utilize exercise to enhance bone mass and strength in the elderly. We recently observed that in senescent animals subject to cyclically applied loading, supplementation with Cyclosporin A (CsA) substantially enhanced the...
Autores principales: | Srinivasan, Sundar, Threet, Dewayne, Worton, Leah E., Ausk, Brandon J., Bain, Steven D., Gardiner, Edith M., Kwon, Ronald Y., Gross, Ted S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880323/ https://www.ncbi.nlm.nih.gov/pubmed/24404194 http://dx.doi.org/10.1371/journal.pone.0084868 |
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