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Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

BACKGROUND: Increased collagen deposition provides physical and biochemical signals to support tumor growth and invasion during breast cancer development. Therefore, inhibition of collagen synthesis and deposition has been considered a strategy to suppress breast cancer progression. Collagen prolyl-...

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Detalles Bibliográficos
Autores principales: Xiong, Gaofeng, Deng, Lei, Zhu, Jieqing, Rychahou, Piotr G, Xu, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880410/
https://www.ncbi.nlm.nih.gov/pubmed/24383403
http://dx.doi.org/10.1186/1471-2407-14-1