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Over-expression of COX-2 mRNA in colorectal cancer

BACKGROUND: Cyclooxygenase-2 (COX-2, PTGS2) is an enzyme involved in the synthesis of prostaglandins and thromboxanes, which are regulators of biologic processes such as inflammation, cell proliferation and angiogenesis. COX-2 over-expression was reported in many (pre) malignant tissues, but data st...

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Detalles Bibliográficos
Autores principales: Roelofs, Hennie MJ, te Morsche, Rene HM, van Heumen, Bjorn WH, Nagengast, Fokko M, Peters, Wilbert HM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880419/
https://www.ncbi.nlm.nih.gov/pubmed/24383454
http://dx.doi.org/10.1186/1471-230X-14-1