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Validation of flow cytometric phospho-STAT5 as a diagnostic tool for juvenile myelomonocytic leukemia

To diagnose juvenile myelomonocytic leukemia (JMML) is sometimes challenging, because around 10% of patients lack molecular abnormalities affecting Ras-MAPK (mitogen-activated protein kinase) pathway and other diseases such as cytomegalovirus infection can mimic clinical signs of JMML. In order to v...

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Detalles Bibliográficos
Autores principales: Hasegawa, D, Bugarin, C, Giordan, M, Bresolin, S, Longoni, D, Micalizzi, C, Ramenghi, U, Bertaina, A, Basso, G, Locatelli, F, Biondi, A, te Kronnie, G, Gaipa, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880439/
https://www.ncbi.nlm.nih.gov/pubmed/24241400
http://dx.doi.org/10.1038/bcj.2013.56