A novel STAT inhibitor, OPB-31121, has a significant antitumor effect on leukemia with STAT-addictive oncokinases

Signal transduction and activator of transcription (STAT) proteins are extracellular ligand-responsive transcription factors that mediate cell proliferation, apoptosis, differentiation, development and the immune response. Aberrant signals of STAT induce uncontrolled cell proliferation and apoptosis...

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Detalles Bibliográficos
Autores principales: Hayakawa, F, Sugimoto, K, Harada, Y, Hashimoto, N, Ohi, N, Kurahashi, S, Naoe, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880446/
https://www.ncbi.nlm.nih.gov/pubmed/24292418
http://dx.doi.org/10.1038/bcj.2013.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880446/
https://www.ncbi.nlm.nih.gov/pubmed/24292418
http://dx.doi.org/10.1038/bcj.2013.63

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