The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy

A major difficulty in the treatment of cancers is the poor response of many tumors to pharmacological regimens. This situation can be accounted for by the existence of a variety of complex mechanisms of chemoresistance (MOCs), leading to reduced intracellular concentrations of active agents, changes...

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Detalles Bibliográficos
Autores principales: Marin, Jose JG, Monte, Maria J, Blazquez, Alba G, Macias, Rocio IR, Serrano, Maria A, Briz, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880477/
https://www.ncbi.nlm.nih.gov/pubmed/24317012
http://dx.doi.org/10.1038/aps.2013.131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880477/
https://www.ncbi.nlm.nih.gov/pubmed/24317012
http://dx.doi.org/10.1038/aps.2013.131

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