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The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy
A major difficulty in the treatment of cancers is the poor response of many tumors to pharmacological regimens. This situation can be accounted for by the existence of a variety of complex mechanisms of chemoresistance (MOCs), leading to reduced intracellular concentrations of active agents, changes...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880477/ https://www.ncbi.nlm.nih.gov/pubmed/24317012 http://dx.doi.org/10.1038/aps.2013.131 |