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Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins

The sequencing of the human genome has fueled the last decade of work to functionally characterize genome content. An important subset of genes encodes membrane proteins, which are the targets of many drugs. They reside in lipid bilayers, restricting their endogenous activity to a relatively special...

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Detalles Bibliográficos
Autores principales: Babcock, Joseph J, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880479/
https://www.ncbi.nlm.nih.gov/pubmed/24241348
http://dx.doi.org/10.1038/aps.2013.142