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Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins
The sequencing of the human genome has fueled the last decade of work to functionally characterize genome content. An important subset of genes encodes membrane proteins, which are the targets of many drugs. They reside in lipid bilayers, restricting their endogenous activity to a relatively special...
Autores principales: | Babcock, Joseph J, Li, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880479/ https://www.ncbi.nlm.nih.gov/pubmed/24241348 http://dx.doi.org/10.1038/aps.2013.142 |
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